![]() ![]() MethodsĮxpression of the periviscerokinin receptor ( Rhimi-CAP 2b R) was investigated throughout the developmental stages of R. microplus, and their cognate receptor only characterized for the last two. These peptides have been identified only in a few tick species, such as Ixodes ricinus, Ixodes scapularis and R. Periviscerokinins (CAP 2b/PVKs) are neuropeptides associated with myotropic and diuretic activities in insects. However, the physiological activity of many neuropeptides is still unknown in ticks. In Ecdysozoa, neuropeptides and their G-protein-coupled receptors play a critical integrative role in the regulation of all physiological processes. The cattle fever tick, Rhipicephalus ( Boophilus) microplus, is a vector of pathogens causative of babesiosis and anaplasmosis, both highly lethal bovine diseases that affect cattle worldwide. ![]()
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